The premonitory phase of migraine is due to hypothalamic dysfunction: revisiting the evidence
Abstract Objective To critically appraise the evidence for and against premonitory symptoms in migraine being due to hypothalamic dysfunction.Discussion Some premonitory symptoms (e.g.fatigue, mood changes, yawning, and food craving) are associated with the physiologic effects of neurotransmitters such as orexins, neuropeptide Y, and dopamine; all